Zopiclone is typically detectable in urine for 24–48 hours after a single dose. Because zopiclone has a short half-life of approximately 3.5–6.5 hours, it clears from blood within 12–24 hours. Hair follicle tests can detect zopiclone for up to 90 days. Zopiclone is a Schedule 4 controlled substance in the UK and is included in extended drug testing panels.
Estimates only. Individual results vary based on metabolism, body weight, hydration, and frequency of use.